Blog posts

How to Measure and Improve ROI in Clinical Research (2021). Logibec. Read the post.

How Patient Recruitment Affects the Bottom Line of a Research Center (2021). Logibec. Read the post.

Accelerate the Research Pipeline with Logibec NOAH and i2b2 (2021) Logibec. Read the post.

How to Preserve Patient Privacy While Maintaining Full Access to EHR? (2021) Logibec. Read the post.

Peer-reviewed Publications

S Kapchinsky,  M Vuda,  K Miguez,  D Elkrief, AR de Souza  ... RT Hepple (2018). Smoke‐Induced Neuromuscular Junction Degeneration Precedes the Fibre Type Shift and Atrophy in Chronic Obstructive Pulmonary Disease. Journal of Physiology, 596(14), 2865-2881. DOI: 10.1113/JP275558

N MacMillan, S Kapchinsky, Y Konokhova, G Gouspillou, R de Sousa Sena ... T Taivassalo (2017). Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease. Frontiers in Physiology, 8, 114. DOI: 10.3389/fphys.2017.00114

H Perrault, R Richard, S Kapchinsky, J Baril, J Bourbeau & T Taivassalo (2016). Addressing Assumptions for the Use of Non-invasive Cardiac Output Measurement Techniques During Exercise in COPD. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(1), 75-81. DOI: 10.3109/15412555.2015.1043985

S Spendiff, M Vuda, G Gouspillou, S Aare, A Perez  … S Kapchinsky  ...  RT Hepple (2016). Denervation Drives Mitochondrial Dysfunction in Skeletal Muscle of Octogenarians. The Journal of Physiology, Stress - Skeletal Muscle, 7361-7379. DOI: 10.1113/JP272487

Y Konokhova, S Spendiff, RT Jagoe, S Aare, S Kapchinsky ...T Taivassalo (2016). Failed Upregulation of TFAM Protein and Mitochondrial DNA in Oxidatively Deficient Fibers of Chronic Obstructive Pulmonary Disease Locomotor Muscle. Skeletal Muscle 6(10). DOI: 10.1186/s13395-016-0083-9

R Hepple, G Gouspillou, S Kapchinsky, N Sgarioto, J Baril ...T Taivassalo (2014). Mitochondrial Functional Alterations in COPD Locomotor Muscle are Independent of Cachexia and Fiber Type Shift. European Respiratory Journal 44, 2146. 

ME Isner‐Horobeti,  L Rasseneur, E Lonsdorfer‐Wolf, S Pascal Dufour, S Doutreleau … S Kapchinsky ... R Richard (2014). Effect of Eccentric Versus Concentric Exercise Training on Mitochondrial Function. Muscle and Nerve 50(5) 803-811. DOI: 10.1002/mus.24215

G Gouspillou, N Sgarioto, S Kapchinsky, F Purves-Smith, B Norris, … RT Hepple (2014). Increased Sensitivity to Mitochondrial Permeability Transition and Myonuclear Translocation of Endonuclease G in Atrophied Muscle of Physically Active Older Humans. The FASEB Journal 28(4). DOI: 10.1096/fj.13-242750

Y Guo, HR Gosker, AMWJ Schols, S Kapchinsky, J Bourbeau, … SNA Hussain (2013). Autophagy in Locomotor Muscles of Patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 188(11). DOI: 10.1164/rccm.201304-0732OC 

R Sena, J Baril, S Kapchinsky, N MacMillan, D Vieira Rocha … J Bourbeau (2012). The Effects of Eccentric and Concentric Exercise Training on Muscle Strength in COPD: Preliminary Results. European Respiratory Journal 40, 482.

MFN. O’Leary, S Kapchinsky, and DA Hood (2007). Effects of Prior Chronic Contractile Activity on Subsequent Denervation-Induced Apoptosis in Skeletal Muscle. The FASEB Journal 21(6). DOI: 10.1152/japplphysiol.00724.2007

Doctoral Thesis

S Kapchinsky (2015). Novel mechanisms and interventions addressing locomotor muscle atrophy and reduced oxidative capacity in severe COPD patients.

Conference Posters and Presentations

S Kapchinsky,  D Mayaki , R Debigare , F Maltais , T Taivassalo , S Hussain (2015). Gene Regulation: MiRNAs and Epigenetics: Regulation of Muscle Atrophy-Related MicroRNAs in Limb Muscles of COPD Patients. Am J Respir Crit Care Med 191.

S Kapchinsky, P Rozakis, N MacMillan, G Gouspillou, TP Jagoe ... T Taivassalo (2014). Eccentric Cycling Improves the Metabolic Profile of Lower Limb Muscle in Severe COPD. Am J Respir Crit Care Med 189.

S Kapchinsky, J Baril , J Laurin, H Perrault, J Bourbeau, T Taivassalo (2010). Reliability of Exercise Cardiac Output Measurement in COPD Using Impedancemetry: Comparison With CO2 And Inert Gas Rebreathing. COPD: Journal of Chronic Obstructive Pulmonary Disease.

Additional Conference Posters and Presentations

S Spendiff, M Vuda, G Gouspillou, S Aare, ME Filion, S Kapchinsky … RT Hepple (2015). Primary versus Secondary Mitochondrial Function Alterations in Aging Muscle. The FASEB Journal.

Y Konokhova , S Spendiff , T Jagoe , M Picard , S Kapchinsky ... T Taivassalo (2013). Mitochondrial DNA Deletions Correspond to High Levels of Oxidative DNA Damage in COPD Skeletal Muscle. ATS International Conference Abstracts: REDOX And Reactive Oxygen Species in Lung and Airway Pathology.

N MacMillan, S Kapchinsky, FM Purves-Smith, N Sgarioto, J Baril ... T Taivassalo (2012). Positives of Negative Work: Eccentric Cycling Effects on Skeletal Muscle in Chronic Obstructive Pulmonary Disease (COPD). ATS International Conference Abstracts: Skeletal Muscle Dysfunction in Chronic Pulmonary Disease: Adaptation or Maladaptation?

RS Sena, J Baril, S Kapchinsky , R Nania, DS Vieira Rocha ... J Bourbeau (2012) Eccentric Cycle Exercise for Patients With Severe COPD: Training Application and Feasibility. ATS International Conference Abstracts: COPD: Functional Assessment and Exercise.

J Baril, S Kapchinsky, J Laurin, C Darauay, R Richard … J Bourbeau (2011) Normal Peak Exercise Cardiac Output Response in Chronic Obstructive Pulmonary Disease (COPD) Patients. ATS International Conference Abstracts: COPD and Cardiovascular Disease.

Academic Background

Additional training

• Project Management Professional (PMP) (2021) The Project Management Institute, PMI

• Scrum Product Owner (2020) Scrum Alliance

• Project Management: Healthcare Projects (2020) LinkedIn Learning

• Design and Interpretation of Clinical Trials (2019) John Hopkins University

• Lead Facilitator Training (2019) UpstartEd

• Project Management Essentials (2018) McGill University

• Artificial intelligence: Implications for business strategy (2018) MIT SLOAN

• Systems Biology Training Program (2010-2014) McGill University